Jorge Oksenberg, Professor

Closed (1) Functional studies on multiple sclerosis genetics

Applications for Fall 2017 are now closed for this project.

The principal aim of our laboratory is to identify the major genetic factors that predispose individuals to autoimmunity and tissue injury in the central nervous system. Our goals are to apply and integrate molecular, immunological, informatic, statistical, and epidemiological experimental approaches, and translate this information into better diagnosis, prognosis, treatment and prevention of multiple sclerosis and other neuroinflammatory diseases. In particular, we extensively use transgenic murine models to understand the contribution of specific genes and pathways to autoimmune demyelination.

The student will perform genotyping of the different mouse strains which includes DNA extraction, PCR screening and gel electrophoresis. The laboratory offers a nurturing and interactive environment to acquire skills in modern genetics research.

Day-to-day supervisor for this project: Alessandro Didonna, Post-Doc

Qualifications: Required: some background in biology and genetics Desirable: some wet lab experience (pipetting, PCR assays)

Weekly Hours: to be negotiated

Off-Campus Research Site: UCSF Mission Bay Campus
675 Nelson Rising Lane
San Francisco, CA 94158, USA

Related website: http://msgenes.ucsf.edu/