Single-cell RNA sequencing and Bulk RNA Sequencing Analysis for Invitro and Invivo Glaucoma Models
John Flanagan, Professor
Optometry
Closed. This professor is continuing with Fall 2024 apprentices on this project; no new apprentices needed for Spring 2025.
This project is centered around RNA sequencing and differential expression analysis in the context of glaucoma research. Specifically, the project aims to compare the gene expression profiles in cell culture and mice models to identify target genes implicated in glaucoma pathogenesis.
Role: Undergraduate students participating in this project will play a crucial role in the analysis of single-cell RNA sequencing data and bulk RNA sequencing data. Their tasks will include data pre-processing, identifying differentially expressed genes, and creating meaningful visualizations to present the results effectively.
Qualifications: Basic biological knowledge, especially in genetics and molecular biology.
Fundamental computational skills, including coding in R, are a must, and the basics of Python and Matlab are optional.
Day-to-day supervisor for this project: Shruthi Karnam, Shubham Maurya, Post-Doc
Hours: 9-11 hrs
Biological & Health Sciences