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Denis Titov - Assistant Adjunct Professor, Nutritional Sciences and Toxicology
Status: Check back for status Weekly Hours: 12 or more hours Location: On Campus
ATP powers most energy-consuming reactions in cells. While ATP has a short half-life, the demand for ATP also fluctuates. Thus, ATP or energy homeostasis in cells needs to be appropriately regulated. ATP homeostasis has to perform at least three tasks: allow energy generation from ATP hydrolysis, maintain stable...
Biological & Health SciencesDenis Titov - Assistant Adjunct Professor, Nutritional Sciences and Toxicology
Status: Full- no new appr needed Weekly Hours: 12 or more hours Location: On Campus
A distinct metabolic phenotype in cancers is the alteration of glucose metabolism. In general, most cells in the body derive their ATP from respiration. However, most cancer cells generate a substantial fraction of their ATP through glycolysis thereby converting their glucose to lactate and exhibit lower respiration activity. The ability...
Biological & Health SciencesDenis Titov - Assistant Adjunct Professor, Nutritional Sciences and Toxicology
Status: Full- no new appr needed Weekly Hours: 12 or more hours Location: On Campus
Aging is the greatest risk factor for numerous chronic conditions such as cancer, cardiovascular disease, and neurodegeneration. Once thought to be an uncontrollable stochastic process due to an accumulation of damage over time, genes and regulatory networks have been discovered that modulate the rate of aging. Supported by data in...
Biological & Health Sciences