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Project Descriptions
Spring 2025

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Showing 3 projects out of 3 found. On page 1 out of 1.
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Developing an assembly and annotation pipeline for gut bacterial genomes

Ashley Wolf - Professor, Public Health

Status: Full- no new appr needed     Weekly Hours: 6-8 hrs     Location: On Campus

Bacteroidetes is one of the main bacterial groups of the human gut microbiome. Although several reference strains related to species such Bacteroides thetaiotaomicron, Bacteroides fragilis and Phocaicola vulgatus have been investigated and even used as model organisms to understand the gut microbiome, strain level diversity is extensive and remains to...

 Biological & Health Sciences

Characterizing novel pathways for sialic acid metabolism in gut bacteria

Ashley Wolf - Professor, Public Health

Status: Full- no new appr needed     Weekly Hours: 9-11 hrs     Location: On Campus

The gut microbiome is a complex community of microbes that have unique enzymatic capabilities. Some gut bacteria metabolize sialic acids that are found in the diet and/or produced by host cells. We have identified putative genes that encode enzymes responsible for sialic acid metabolism. This project will use cloning...

 Biological & Health Sciences

Gut bacterial metabolism

Ashley Wolf - Professor, Public Health

Status: Full- no new appr needed     Weekly Hours: to be negotiated     Location: On Campus

Dietary ingredients can provide fuel to the gut microbiome and influence the abundance of particular bacterial species in the gut. During heating steps in food processing, Maillard reaction products (MRPs) are formed from non-enzymatic reaction between amino acids and reducing sugars. As one of the MRPs, ε-fructoselysine (FL...

 Biological & Health Sciences

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