URAP

Ian Swinburne - Professor, Molecular and Cell Biology

Status: Current Term Now Closed     Weekly Hours: 12 or more hours     Location: On Campus

Day-to-day health of the eye relies on the accumulation of the eye’s internal fluid being balanced by release of excess fluid or pressure. The fluid’s flow and pressure help keep the eye’s tissues healthy and the correct size and shape. Glaucoma, a leading cause of blindness, is usually...

Ian Swinburne - Professor, Molecular and Cell Biology

Status: Full- no new appr needed     Weekly Hours: 9-11 hrs     Location: On Campus

Cells integrate extracellular cues (biochemical or mechanical signals) in order to direct specific cellular and tissue wide responses. The correct functioning of organs depends on this communication between cells and their surrounding environment. However, our understanding of how external mechanical inputs, such as increased pressure, direct cell function in health...

Ian Swinburne - Professor, Molecular and Cell Biology

Status: Full- no new appr needed     Weekly Hours: 12 or more hours     Location: On Campus

Auditory and vestibular senses are classic and essential senses of the body. The inner ear’s development, or morphogenesis, is a complex and well-regulated process that is guided by cell communication or signaling pathways. When signaling pathways become dysregulated, it often leads to deformities and/or diseases. And in the...

Ian Swinburne - Professor, Molecular and Cell Biology

Status: Full- no new appr needed     Weekly Hours: 12 or more hours     Location: On Campus

Most life processes involve cells managing fluids. Our sense of hearing and balance depend on the tight regulation of inner ear fluid (endolymph) volume and pressure. Increased endolymph volume and pressure can lead to the development of deafness and balance disorders. Our previous work in zebrafish embryos has shown that...