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Robert Tjian - Professor, Molecular and Cell Biology
Status: Full- no new appr needed Weekly Hours: 12 or more hours Location: On Campus
Regulation of DNA transcription is one of the mechanisms at the core of cellular identity establishment and maintenance. Our lab is interested in studying the proteins that operate such regulation, transcription factors (TFs). Uncovering TFs DNA binding specificity is key to understand how certain TFs switch on (or off) some...
Robert Tjian - Professor, Molecular and Cell Biology
Status: Full- no new appr needed Weekly Hours: 12 or more hours Location: On Campus
In live cells, biomolecules are in constant motion, driven by a range of specific and nonspecific interactions. These dynamic behaviors are key to understanding the in vivo properties and functional mechanisms of biomolecules. Single-molecule microscopes, which enable the tracking of individual target molecules, have opened new frontiers in this...
Robert Tjian - Professor, Molecular and Cell Biology
Status: Full- no new appr needed Weekly Hours: 12 or more hours Location: On Campus
Regulation of DNA transcription is one of the mechanisms at the core of cellular identity establishment and maintenance. Our lab is interested in studying the nuclear dynamics of the proteins that operate such regulation, transcription factors (TFs). To this aim we typically fuse a TF of interest with either Halo...