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Project Descriptions
Fall 2025

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Showing 2 projects out of 2 found. On page 1 out of 1.
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Single Molecule Protein Folding with DNA Origami in Optical Tweezers

Carlos Bustamante - Professor, QB3: Quantitative Biomedical Research

Status: Current Term Now Closed     Weekly Hours: 9-11 hrs     Location: On Campus

Optical tweezers are a method to exert force on individual molecules and directly measure forces generated during their biochemical reactions.[1] Molecules are tethered between double strand DNA (dsDNA) handles to micron-sized beads that are held in optical traps. The flexibility of these handles limits the resolution of optical...

Single Molecule Nucleosome Unwrapping with DNA Origami in Optical Tweezers

Carlos Bustamante - Professor, QB3: Quantitative Biomedical Research

Status: Full- no new appr needed     Weekly Hours: 9-11 hrs     Location: On Campus

Optical tweezers are a method to exert force on individual molecules and directly measure forces generated during their biochemical reactions.[1] Molecules are tethered between double strand DNA (dsDNA) handles to micron-sized beads that are held in optical traps. The flexibility of these handles limits the resolution of optical...

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