Project 4: Metabolic Adaptions following Traumatic Brain Injury
George A. Brooks, Professor
Integrative Biology
Closed. This professor is continuing with Fall 2023 apprentices on this project; no new apprentices needed for Spring 2024.
The applicant will work with GSI/GSR Austin Peck on the discovery of metabolic signaling following Traumatic Brain Injury (TBI) to rats and mice. Responsibilities will run the full gambit from assisting in animal handling (including care and feeding), to data collection and analysis. Injured and uninjured control animals will be subjected to behavioral tests as well as numerous tests on living and postmortem animals. The techniques will include aspects of MRI on live animals and confocal microscopy on histological sections. As well, metabolic signaling pathways will be tracked via gene array analysis and Western blotting and Mass spectrometry. Microscopy and polarography studies will be used to determine the effects TBI on brain and muscle mitochondrial morphology and function.
Qualifications: IB 132 and IB 123A concurrent. Students will need to take instruction in safe laboratory practices and humane laboratory animal care and handling.
Hours: to be negotiated
Related website: https://ib.berkeley.edu/people/faculty/brooksg
Related website: http://www.chori.org/Principal_Investigators/Kuypers_Frans_A/kuypers_overview.html