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Berkeley University of California

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Project Descriptions
Fall 2026

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Defining Cellular and Molecular Mechanisms of Neuroprotection in Glaucoma

Karsten Gronert, Professor  
Optometry  

Open. Apprentices needed for the fall semester. Enter your application online beginning August 21st. The deadline to apply is Monday, August 31st, 4pm.

We are focused on elucidating the role and molecular mechanisms of neuroprotective lipid mediators essential for inhibiting the death of retinal ganglion cells in glaucoma. We use wide range of techniques in lab including single-cell transcriptomics, morphOMICs, and lipidomics as a tool to investigate and understand the protective mechanisms in glaucoma pathogenesis.

Role: 1. Perform Immunostaining: The role involves preparing tissue samples for analysis by performing immunostaining on both sectioned and whole-mount tissues.

2. Acquire High-Quality Microscopy Data: Use confocal microscopy to capture images of stained tissues.

3. Conduct Data Analysis: Analyze large datasets derived from microscopy images. You will use R, Python, and MATLAB to process and interpret this data.

4. Collaborate with Researchers: Act independent, assisting postdoctoral fellows and graduate students with their data generation and analysis needs.

Qualifications: Highly motivated, responsible, mature, and independent student with a long-term commitment and basic knowledge of molecular biology. Coding in R and Python are essential with optional basic knowledge in Matlab.

Day-to-day supervisor for this project: Shubham Maurya or Shruthi Karnam, Post-Doc

Hours: 12 or more hours

Related website: https://gronertlabberkeley.org/

 Biological & Health Sciences

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