Evaluating leaderless translation in mycobacteria (position filled)
Babak Javid, Professor
Medicine/Experimentsl Medicine
Closed. This professor is continuing with Fall 2024 apprentices on this project; no new apprentices needed for Spring 2025.
Almost everything known about bacterial protein synthesis is from the study of "canonical" mRNAs in E. coli and other model organisms. However, many bacteria translate non-canonical mRNAs. A quarter of mRNAs in mycobacteria lack 5' UTRs -- but the "rules" governing leaderless translation are not fully understood. This project will explore genetics of leaderless vs. canonical translation in mycobacteria.
Please note, this project will either start late in Fall term or Spring term. Selection of students will be via the formal application process.
Qualifications: Experience in cloning/molecular biology highly desirable.
Day-to-day supervisor for this project: Caldwell Sarah Feid
Hours: to be negotiated
Off-Campus Research Site: UCSF -- Zuckerberg San Francisco General Hospital Division of Experimental Medicine San Francisco
Related website: http://
Biological & Health Sciences