URAP

Iain Clark - Professor, Bioengineering

Status: Full- no new appr needed     Weekly Hours: 9-11 hrs     Location: On Campus

This project aims to hack an Illumina HiSeqX to create an open-source sequencing platform for spatial analysis of single cells (RNA-seq, DNA-seq, etc on tissue). The HiSeqX contains advanced fluidics and optics made for Next Generation Sequencing (NGS). A community of hackers is working to repurpose these...

Iain Clark - Professor, Bioengineering

Status: Full- no new appr needed     Weekly Hours: 12 or more hours     Location: On Campus

You will assist a PhD student mentor in developing a technology to isolate cells based on DNA markers of HIV. This technique builds off of Clark et al.’s 2023 publication “HIV silencing and cell survival signatures in infected T cell reservoirs.” This project will involve microfluidics, flow cytometry, and...

Iain Clark - Professor, Bioengineering

Status: Full- no new appr needed     Weekly Hours: 9-11 hrs     Location: On Campus

We recently developed a molecular method that categorizes the cellular connections and transcriptional profiles of glial cells in the mouse brain. The data from this technique can be represented as a highly connected network. The goal of this project is to discover ligand-receptor interactions that promote inflammation in the...

Iain Clark - Professor, Bioengineering

Status: Full- no new appr needed     Weekly Hours: 9-11 hrs     Location: On Campus

We recently developed a molecular method that categorizes the cellular connections and transcriptional profiles of glial cells in the mouse brain. The data from this technique can be represented as a highly connected network. The goal of this project is to discover ligand-receptor interactions that promote inflammation in the...

Amy Herr - Professor, Bioengineering

Status: Current Term Now Closed     Weekly Hours: 9-11 hrs     Location: On Campus

We are addressing a major blocker in microfluidic design: the macro-to-micro interface. Here, we consider how to precisely move and situation an array of single nuclei (from single mammalian cells). We have a vacuum-driven manifold that does the job, but we need to understand best operating parameters...