URAP

Michael Shapira - Professor, Integrative Biology

Status: Full- no new appr needed     Weekly Hours: 12 or more hours     Location: On Campus

Toxins play important roles in inter-species interactions, and the ability to overcome them can open new niches. The potential of animal genomes to facilitate such adaptations is limited; instead, toxin resistance in animals is often provided by gut bacteria. Human activity and industry has dramatically increased the prevalence of...

Michael Shapira - Professor, Integrative Biology

Status: Full- no new appr needed     Weekly Hours: 12 or more hours     Location: On Campus

Animal microbiotas are increasingly recognized as essential for host health. The gut microbiota is the richest, and was shown to contribute to diverse host functions. Perturbations in microbiota composition are associated with human disease, raising interest in manipulating the microbiota to promote healthier living or treat pathology. However, current understanding...

Michael Shapira - Professor, Integrative Biology

Status: Full- no new appr needed     Weekly Hours: 12 or more hours     Location: On Campus

Aging involves a multi-system physiological deterioration. In addition to affected tissues, and likely as a consequence, aging also affects the gut microbiota, an extensive microbial community which contributes to diverse host functions. Imbalances in microbiota composition, or dysbiosis, are often associated with pathology, and recent reports indicate that aging...