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Project Descriptions
Spring 2025

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Showing 4 projects out of 4 found. On page 1 out of 1.
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Computational Modeling and Deep Learning of Heart Tissue Dynamics: Studying the Interplay between Excitation Waves, Calcium, and Mechanical Contraction

Jan Christoph - Professor, UC San Francisco

Status: Current Term Now Closed     Weekly Hours: 12 or more hours     Location: On Campus

Our group studies heart rhythm disorders, such as ventricular tachycardia or atrial fibrillation, using computer simulations and imaging. Heart rhythm disorders are associated with abnormal electrophysiological excitation wave phenomena in the heart muscle, which can take on complex pattern-forming and self-organizational spatio-temporal dynamics. The excitation triggers intracellular...

 Engineering, Design & Technologies   Biological & Health Sciences   Mathematical and Physical Sciences

3D Image Processing of Optical and Ultrasound Imaging Data

Jan Christoph - Professor, UC San Francisco

Status: Current Term Now Closed     Weekly Hours: 12 or more hours     Location: On Campus

Our group develops computational and experimental methods for the imaging of intact, isolated hearts ex vivo. We produce 3D imaging data using fluorescence and ultrasound imaging, see https://arxiv.org/abs/2307.07943, and we combine this data to obtain high-resolution visualizations of beating hearts and heart rhythm disorders...

 Engineering, Design & Technologies   Biological & Health Sciences   Mathematical and Physical Sciences

Development of Computer Vision Techniques for use with a Multi-Camera Panoramic Fluorescence Imaging System for Cardiac Imaging

Jan Christoph - Professor, UC San Francisco

Status: Current Term Now Closed     Weekly Hours: 12 or more hours     Location: On Campus

Are you a computer vision enthusiast and are you interested in applying your skills in biological research? Our group develops computational and experimental methods for the imaging of the heart and heart rhythm disorders. We have developed a novel panoramic high-speed fluorescence imaging setup for the imaging of the...

 Engineering, Design & Technologies   Biological & Health Sciences   Mathematical and Physical Sciences

Simulation of Cardiac Tissue Development

Jan Christoph - Professor, UC San Francisco

Status: Full- no new appr needed     Weekly Hours: 12 or more hours     Location: On Campus

Our group studies the heart from a complex biological system's perspective und we use computer simulations to study cardiac dynamics during disease and development. In the heart, electrical excitation propagates from cell to cell through ion channels and triggers mechanical contraction and deformation in each cell. This leads to waves...

 Engineering, Design & Technologies   Biological & Health Sciences   Mathematical and Physical Sciences

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